OP01.08: Association between placental volume and cell-free DNA assay failure

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Cell-free DNA release by mouse placental explants

Although suggested that "fetal" cell-free DNA (cfDNA) is derived from trophoblast cells, the exact origin is unclear. The studies in this report sought to demonstrate that placental tissue releases cfDNA in parallel with cell death, that the size range of cfDNA is similar to that found in maternal plasma, and that the cfDNA fragments are able to stimulate a proinflammatory cytokine response. Pl...

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association between papp-a and placental thickness

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Cell - free DNA: بیومارکر نوین تشخیص آزمایشگاهی

به انواع مختلف اسیدهای نوکلئیک آزاد در پلاسما شامل قطعات DNA ژنومی،DNA میتوکندریایی، DNA و mRNA های ویروسی و همچنین انواع miRNA اصطلاحا Cell–free nucleic acid گفته می شود. بخش مهمی از این اسیدهای نوکلئیک آزاد در پلاسما را Cell–free DNA (cfDNA) تشکیل می دهد. cfDNA به صورت قطعاتی با وزن مولکولی حدود KB 21-0.18 در سرم یا پلاسمای افراد سالم و افراد مبتلا به بسیاری از بیماری ها قابل تشخیص هستند. ...

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Association between PAPP-A and placental thickness

BACKGROUND Measuring of maternal serum pregnancy-associated plasma protein-A (PAPP-A) in first trimester can be a way for early detection of adverse prenatal outcome due to faulty placenta. OBJECTIVE The aim was to Determination of association between placental thickness in second trimester with low level of PAPP-A in first trimester. MATERIALS AND METHODS In this cohort study, serum PAPP-A...

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Association between calcifying nanoparticles and placental calcification

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ژورنال

عنوان ژورنال: Ultrasound in Obstetrics & Gynecology

سال: 2018

ISSN: 0960-7692

DOI: 10.1002/uog.19398